Publications
Correction of {Delta}F508-CFTR trafficking defect by the bioavailable compound glafenine.
Robert R, Carlile GC, Liao J, Balghi H, Lesimple P, Liu N, Kus B, Rotin D, Wilke M, de Jonge HR, Scholte BJ, Thomas DY, Hanrahan JW.
Molecular Pharmacology 2010 March 3.
Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4-2 using proteome arrays.
Persaud A, Alberts P, Amsen EM, Xiong X, Wasmuth J, Saadon Z, Fladd C, Parkinson J, Rotin D.
Mol Syst Biol. 2009 Dec 1;5:333
Functional rescue of DeltaF508-CFTR by peptides designed to mimic sorting motifs.
Chiaw PK, Huan LJ, Gagnon S, Ly D, Sweezey N, Rotin D, Deber CM, Bear CE.
Chem Biol. 2009 May 29;16(5):520-30.
The inositol phosphatase MTMR4 is a novel target of the ubiquitin ligase Nedd4.
Plant PJ, Correa J, Goldenberg N, Bain J, Batt J.
Biochem J. 2009 Apr 1;419(1):57-63.
High-content functional screen to identify proteins that correct F508del-CFTR function.
Trzcinska-Daneluti A, Ly D, Huynh L, Jiang C, Fladd C, Rotin D.
Mol Cell Proteomics. 2008 Dec 15
Ubiquitination screen using protein microarrays for comprehensive identification of Rsp5 substrates in yeast.
Gupta R, Kus B, Fladd C, Washmuth J, Tonikian R, Sidhu S, Krogan NJ, Parkinson, J, Rotin D
Mol Syst Biol. 2007;3:116.
High-throughput assays of phagocytosis, phagosome maturation, and bacterial invasion.
Steinberg, BE, Scott CC, Grinstein S.
Am J Physiol Cell Physiol. 2007 Feb;292(2):C945-52.
A high throughput screen to identify substrates for the ubiquitin ligase Rsp5.
Kus B, Gajadjar A, Stanger K, Cho R, Sun W, Rouleau N, Lee T, Chan D, Wolting C, Edwards A, Bosse R, Rotin D.
J Biol Chem. 2005 Aug 19;280(33):29470-8